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It would reduce the cost and effort to create and maintain bathrooms.
It can lead to sexual harassment
It can eliminate discrimination on people outside the gender binary.
All unisex bathrooms should only have 1 toilet or urinal.
Many bathrooms are differentiated by sex because it takes men less time to use the bathroom in comparison to women.
most men don't know how frequently women get hit on by random strangers. Not to mention the risk of rape, this will make things easier and possibly provide temptation to act for people who don't have a lot of self control.
Would a woman dare go to a bathroom in a bar, a football game?
If most people do not want this then they shouldn't.