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From an evolutionary perspective, the meaning of life is to pass on your genes to your offsprings.
meaning is subjective and any human being can attribute different meaning to its life, thus each life means something to at least someone
We can create our own meaning through aspirations and objectives.
You do not need a god-given purpose to create change in the lives of yourself and others. In fact, being free of a deterministic destiny means that your actions are more meaningful, because they were the result of your own personal choices, instead of some unchanging pre-determined fate.
You're begging the obvious. Looking for meaning is a trait human ancestors evolved throughout millions of years to survive. That's why a healthy adult is always driven by a goal. The Universe doesn't "think", why would you believe that random chance was acting in a grand scheme of things.
meaning is subjective and any human being can attribute different meaning to its life, since thre isn't a higher entity that could give life a general meaning