Playing the same tone on the violin or on the piano does not sound the same. Thus we should not limit us only to tones (specific pitches) but also consider all possible instruments and their combinations.
We have a limited range of hearing, and a limited time in which to hear. I can therefore conclude that there will be a limit upon the amount of music one might produce.
but what we consider as music,not noise, stays on limited frequency range thus not all frequency combinations felt pleasant. the combination can be calculated by rhythmical possibilities multiply harmonic possibilities.
This is subjective. Compare classical music to dubstep for instance. Also, we can still create pleasant combinations of notes. I'd recommend that you watch Vsauce's video "Will we ever run out of music?".